对小儿心律失常患儿治疗中小剂量胺碘酮维持治疗下取得的效果，分析药物应用下患儿甲状腺激素水平变化。

选取2016年8月至2017年8月临朐县中医院收治的小儿心律失常患儿116例为研究对象，根据随机数字表法随机分为对照组和观察组，每组58例。分别选择盐酸普罗帕酮片、小剂量盐酸胺碘酮治疗，对两组患儿心律异常治疗效果观察，比较治疗前后甲状腺激素水平变化以及用药不良反应情况。

心律失常治疗效果观察，观察组患儿治疗有效率(96.55%)与对照组(86.21%)，差异有统计学意义(P<0.05)。甲状腺激素水平观察，治疗前后两组患儿各指标比较，差异均无统计学意义(P>0.05)。用药不良反应发生率，观察组(5.17%)与对照组发生率(17.24%)，差异有统计学意义(P<0.05)。

小儿心律失常患儿临床治疗中，药物选择小剂量胺碘酮，对改善心律失常症状有积极作用，不良反应发生率较低，且对患儿甲状腺激素水平无明显影响，应在临床实践中推广应用。

To evaluate the effect of the treatment of children with arrhythmia in the treatment of middle and small dose amiodarone, and to analyze the changes of thyroid hormone levels in children with drug use.

The 116 children with arrhythmia treated in the Chinese Hospital of Linyi County from August 2016 to August 2017 were selected as study subjects. According to the random number table method, they were randomly divided into a control group and an observation group, 58 cases in each group. Select propafenone hydrochloride tablets and small doses of amiodarone hydrochloride to treat the effects of abnormal heart rhythm in the two groups of patients.Compare the changes of thyroid hormone levels and adverse drug reactions before and after treatment.

The effect of arrhythmia treatment was observed, the effective rate of treatment in the observation group(96.55%)was compared with the control group(86.21%), and the difference was statistically significant(P<0.05). There was no significant difference in thyroid hormone levels between the two groups before and after treatment(P>0.05). The incidence of adverse drug reactions(ADR)in the observation group(5.17%)was significantly higher than that in the control group(17.24%), and the difference was statistically significant.

In the treatment of children with arrhythmia, small dose of amiodarone has positive effect on improving the symptoms of arrhythmia, the incidence of adverse reaction is low, and there is no obvious effect on the level of thyroid hormone in children.It should be popularized and applied in clinical practice.