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中华心脏与心律电子杂志 ›› 2017, Vol. 05 ›› Issue (01) : 31 -34. doi: 10.3877/cma.j.issn.2095-6568.2017.05.009

所属专题: 文献

论著

平板运动试验假阳性的影响因素及临床价值
王岚1, 郭丹杰1,(), 牛亚芊芊1, 薛琳1, 张天宏1, 韩春颖1   
  1. 1. 100044 北京,北京大学人民医院心血管内科;急性心肌梗死早期预警和干预北京市重点实验室;北京大学人民医院心血管转化医学研究中心
  • 出版日期:2017-03-25
  • 通信作者: 郭丹杰

Influencing factors of false positive in treadmill exercise test

Lan Wang1, Danjie Guo1,(), Qianqian Niuya1, Lin Xue1, Tianhong Zhang1, Chunying Han1   

  1. 1. Department of Cardiology, Peking University People′s Hospital, Beijing, China; Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People′s Hospital, Beijing, China; Center for Cardiovascular Translational Research, Peking University People′s Hospital, Beijing, 100044 China
  • Published:2017-03-25
  • Corresponding author: Danjie Guo
  • About author:
    Corresponding auther: Guo Danjie, Email:
引用本文:

王岚, 郭丹杰, 牛亚芊芊, 薛琳, 张天宏, 韩春颖. 平板运动试验假阳性的影响因素及临床价值[J/OL]. 中华心脏与心律电子杂志, 2017, 05(01): 31-34.

Lan Wang, Danjie Guo, Qianqian Niuya, Lin Xue, Tianhong Zhang, Chunying Han. Influencing factors of false positive in treadmill exercise test[J/OL]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2017, 05(01): 31-34.

目的

探讨平板运动试验假阳性的影响因素。

方法

入选平板运动试验阳性且1个月内行冠状动脉造影的患者222例,根据是冠脉造影结果分为冠心病组(n=143)及非冠心病组(n=79)。收集两组患者的一般情况(年龄、性别、体重指数、吸烟、家族史),合并疾病,冠脉病变情况,超声心动图以及平板运动试验结果并进行多因素回归分析。

结果

多因素logistics回归分析结果显示女性(P=0.003,OR=11.112,95%CI2.258~54.784)、低龄(P=0.016,OR=0.916,95%CI 0.854~0.984)、Bruce分级(P=0.006,OR=3.453,95%CI 1.424~8.373)及射血分数(P=0.029,OR=1.103,95%CI 1.010~1.204)是平板运动试验假阳性的独立影响因素。

结论

女性、低龄、较高的Bruce分级和射血分数是平板运动试验假阳性的独立影响因素,而冠心病其它危险因素(如肥胖、吸烟、家族史、糖尿病、高血压)及平板运动试验其它参数(ST段压低程度及持续时间、心率与血压反应、ST/HR)不是平板运动试验假阳性的独立影响因素。

Objective

To explore the influencing factors of false positive in treadmill exercise test.

Methods

222 treadmill exercise testing positive patients who were undergone coronary angiography within 1 month were studied. Patients were divided into two groups: coronary heart disease group (CHD group, n=143) and non coronary heart disease group (non CHD group, n=79). Clinical manifestations, combined diseases, coronary arteries situations, ultracardiography and treadmill exercise testing datas of these patients were collected and analyzed.

Results

Female gender (P=0.003, OR=11.112, 95%CI 2.258-54.784), age (P=0.016, OR=0.916, 95%CI 0.854-0.984), Bruce level (P=0.006, OR=3.453, 95%CI 1.424-8.373) and ejective fraction (P=0.029, OR=1.103, 95%CI 1.010-1.204) were independent influencing factors of treadmill exercise testing false positive.

Conclusion

Female gender, age, Bruce level and ejective fraction were independent influencing factors of treadmill exercise testing false positive. Meanwhile other atherosclerosis risk factors and parameters of exercise testing (besides Bruce level) could not provided reference to the judgement of false positive.

表1 两组患者一般临床资料比较
表2 两组患者平板运动试验结果比较
表3 平板运动试验假阳性预测因素的二元Logistic回归分析结果
[1]
Fihn SD, Gardin JM, Abrams J, et al. 2012 ACCF/AHA/ACP/AATS/PCNA /SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons[J]. J Am Coll Cardiol, 2012, 60(24): e44-e164.
[2]
Balady GJ, Arena R, Sietsema K, et al. Clinician’s guide to cardiopulmonary exercise testing in adults: A scientific statement from the American Heart Association[J]. Circulation, 2010, 122: 191-225.
[3]
Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease[J]. Am J Cardiol, 1983. 51: 606-607.
[4]
Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension[J]. Blood Press, 2014, 23(1): 3-16.
[5]
王翀,孙宏泰,王盛宇.156例平板运动试验与冠状动脉造影结果对照分析[J]. 中国心血管病研究,2008,6(1):52-54.
[6]
刘军,林靖宇.平板运动试验在冠心病诊断中的相关性研究[J]. 中国临床医学,2015,22(5):628-630.
[7]
Mieres JH, Shaw LJ, Arai A, et al. Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease: Consensus statement from the Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, Council on Cardiovascular Radiology and Intervention, American Heart Associatio[J]. Circulation, 2005, 111(5): 682-696.
[8]
Fletcher GF, Mills WC, Taylor WC. Update on exercise stress testing[J]. Am Fam Physician, 2006, 74(10): 1749-1754.
[9]
Sun JL, Gao GL, Zhao Y, et al. Elderly patients and coronary heart disease on response to treadmill exercise test[J]. Cell Biochem Biophys, 2013, 67(3): 965-968.
[10]
Blaha MJ, Hung RK, Dardari Z, et al. Age-dependent prognostic value of exercise capacity and derivation of fitness-associated biologic age[J]. Heart, 2016, 102(6): 431-437.
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