Effect of amiodarone combined with metoprolol tartrate on acute myocardial infarction complicated with rapid arrhythmia

doi:10.3877/cma.j.issn.2095-6568.2018.01.008

Abstract

Abstract:

Objective

To evaluate the effect of amiodarone combined with metoprolol tartrate on acute myocardial infarction complicated with rapid arrhythmia.

Methods

A total of 130 patients with acute myocardial infarction complicated with tachyarrhythmia were divided into control group (65 cases) and observation group (65 cases) according to the treatment scheme. The control group received amiodarone treatment, while the observation group received amiodarone combined with metoprolol tartrate. The therapeutic effects, adverse reactions and cardiac function indexes (LVESD, LVEDD, HR, LVEF) before and after treatment were compared between the two groups.

Results

The total effective rate of the observation group was 92.31%, higher than that of the control group 73.85% (P<0.05), the LVEF of the observation group was higher than that of the control group (P<0.05), and the HR, LVESD and LVEDD of the observation group were lower than that of the control group (P<0.05).

Conclusion

In the treatment of acute myocardial infarction complicated with tachyarrhythmia, amiodarone combined with metoprolol tartrate can improve cardiac function with significant efficacy and high safety.

Key words: Amiodarone, Acute myocardial infarction, Rapid arrhythmia, Metoprolol tartrate

Ruimin Li, Xia Wang. Effect of amiodarone combined with metoprolol tartrate on acute myocardial infarction complicated with rapid arrhythmia[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2018, 06(01): 22-24.

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Figures/Tables 2

References 9

[1]	阎雪. 循证护理在急性心肌梗死并发心律失常患者中的应用[J]. 中国循证心血管医学杂志，2016, 8(8): 995-996.
[2]	陈卓宏，张朝勇，朱瓦力，等. 酒石酸美托洛尔联合盐酸胺碘酮治疗急性心肌梗死合并室性心律失常的研究[J]. 中国社区医师，2018, 34(3): 29-30.
[3]	吴艳华. 胺碘酮联合美托洛尔治疗老年冠心病并发心律失常的临床观察[J]. 中国医药导报，2013, 22(29): 76-78.
[4]	刘西方. 胺碘酮联合美托洛尔对急性心肌梗死并发快速心律失常患者心功能恢复的影响[J]. 药品评价，2017, 14(11): 51-54.
[5]	杜翠娟. 胺碘酮与美托洛尔联合用药对急性心肌梗死并发快速心律失常控制效果[J]. 中国卫生工程学，2017, 16(3): 382-383, 386.
[6]	王晋华. 试论小剂量胺碘酮联合酒石酸美托洛尔对老年心律失常患者的治疗效果[J]. 中国卫生标准管理，2016, 7(6): 96-97.
[7]	李莉娟，张冬惠，王绍谦，等. 胺碘酮联合美托洛尔治疗冠状动脉粥样硬化性心脏病并发快速心律失常疗效观察[J]. 新乡医学院学报，2014, 31(2): 120-122.
[8]	何小君，罗贵全. 稳心颗粒与胺碘酮联合酒石酸美托洛尔对冠心病心律失常患者心功能及血液流变学的影响[J]. 实用心脑肺血管病杂志，2017, 25(9): 137-139.
[9]	高波，许红阳. 胺碘酮联合β受体阻滞剂治疗急性心肌梗死并发快速心律失常的疗效观察[J]. 中西医结合心脑血管病杂志，2016, 14(8): 882-884.

组别	例数	无效	有效	显效	总有效
对照组	65	17(26.15)	22(33.85)	26(40.00)	48(73.85)
观察组	65	5(7.69)	22(33.85)	38(58.46)	60(92.31)
χ²值	?	?	?	?	7.879
P值	?	?	?	?	0.005

组别	例数	无效	有效	显效	总有效
对照组	65	17(26.15)	22(33.85)	26(40.00)	48(73.85)
观察组	65	5(7.69)	22(33.85)	38(58.46)	60(92.31)
χ²值	?	?	?	?	7.879
P值	?	?	?	?	0.005

组别	时间	例数	HR(次/min)	LVEF(%)	LVESD(mm)	LVEDD(mm)
对照组	治疗前	65	144.56±14.53	34.86±3.61	52.97±5.03	62.15±5.94
对照组	治疗后	65	94.85±7.74^a	40.69±4.49^a	44.98±4.26^a	51.97±4.96^a
观察组	治疗前	65	145.04±14.82	35.09±3.52	53.62±5.11	61.98±5.87
观察组	治疗后	65	78.36±6.59^ab	51.87±5.32^ab	37.25±3.96^ab	40.82±4.16^ab

组别	时间	例数	HR(次/min)	LVEF(%)	LVESD(mm)	LVEDD(mm)
对照组	治疗前	65	144.56±14.53	34.86±3.61	52.97±5.03	62.15±5.94
对照组	治疗后	65	94.85±7.74^a	40.69±4.49^a	44.98±4.26^a	51.97±4.96^a
观察组	治疗前	65	145.04±14.82	35.09±3.52	53.62±5.11	61.98±5.87
观察组	治疗后	65	78.36±6.59^ab	51.87±5.32^ab	37.25±3.96^ab	40.82±4.16^ab

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