To retrospectively summarize the complications associated with cardiac resynchronization therapy (CRT) in a single center in order to provide relevant experience for the clinical management of CRT patients.

This study is a retrospective study. Patients with heart failure who underwent CRT implantation in the Department of Cardiovascular Medicine, The First Affiliated Hospital of Xinjiang Medical University from June 2009 to June 2021 were included. The patients were divided into cardiac resynchronization therapy defibrillator (CRT-D) and cardiac resynchronization therapy pacemaker (CRT-P) according to the type of implanted device. In the CRT-P group, the failure of left ventricular lead implantation, diaphragm muscle stimulation, coronary venous system injury and other related complications were analyzed, and the reasons for the complications were recorded.

A total of 469 patients were enrolled, including 359 males (359/469, 76.55%), age (62.31±11.69) years, preoperative mean left ventricular ejection fraction was 34.76%±7.96%, preoperative mean QRS duration was (161.82±30.57) ms. The success rate of left ventricular lead implantation was 95.1% (446/499), intraoperative diaphragm stimulation in 2 cases (0.43%); acute left heart failure in 3 cases (6.40%); coronary vein dissection in 15 cases (3.19%). Hematoma occurred in 4 cases (0.85%), and lead dislocation in 10 cases (2.13%), including acute dislocation in 2 cases (20%), subacute dislocation in 4 cases (40%), and delayed dislocation in 4 cases (40%).

The risk of complications related to CRT is high, and at the same time, we should be alert and rule out the possibility of related postoperative complications.