Abstract:
Objective To study the difference of brachial - ankle pulse wave conduction velocity (baPWV) between young essential hypertensive and normal blood pressure people, and to explore the correlation of baPWV with cardiovascular risk factors.
Method Enrolled 120 newly diagnosed hypertension outpatients in Changping Traditonal Chinese Medicine Hospital during May 2015 to December 2016, as hypertension group.and 120 young healthy normal blood pressure people of medical examination center as non-hypertension group .Collected the questionnaire, and test of liver and kidney function, blood lipids, blood glucose, uric acid, urine trace albumin and baPWV respectively.analyzed the baPWV of two groups, and the baPWV by blood pressure grades. Multiple linear regression analysis to explicit the related factors of baPWV in young hypertension patients.
Results (1) the baPWV in hypertension group was higher than in non-hypertensive group with statistically significant [right baPWV: (1 596.65±122.35) vs (1 350.95±63.37), P<0.05; left baPWV: (1 605.70±147.38) vs (1 340.60±64.03), P<0.05]; (2)in hypertension group, the baPWV increased with the blood pressure grade (Grade- 3 hypertension baPWV>Grade-2 hypertension baPWV>Grade-1 hypertension baPWV); (3) there was a correlation between baPWV and systolic blood pressure, diastolic blood pressure and urinary trace albumin (P<0.05), and multiple linear-regression analysis suggested that blood pressure was a related factor affecting baPWV.
Conclusion The baPWV in hypertension group was higher than that in the non-hypertension group, suggested that early blood vessel damage was present in young hypertension patients, and the baPWV also increased as the blood pressure level increasing.Blood pressure is associated with the baPWV, the positive control of hypertension, could improve the baPWV, the arterial stiffness, and prevent the cardiovascular disease in advance.
Key words:
Hypertension,
BaPWV,
Cardiovascular risk factors,
Vascular stiffness
Yayan Zhang, Juxin Wang, Ting Li. Analysis of the relationship between pulse wave velocity and cardiovascular risk factors in young patients with essential hypertension[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2017, 05(04): 200-204.