Effect of bisoprolol combined with benazepril on ventricular arrhythmia after intracerebral hemorrhage

doi:10.3877/cma.j.issn.2095-6568.2018.02.016

Abstract

Abstract:

Objective

To analyze the effect of bisoprolol combined with benazepril on ventricular arrhythmia after intracerebral hemorrhage.

Methods

Sixty patients with ventricular arrhythmia after intracerebral hemorrhage admitted to Rongcheng People's Hospital from May of 2016 to June of 2017 were randomly divided into control group and research group. The control group was treated with bisoprolol and the study group was treated with bisoprolol combined with benazepril. The heart rate and the number of ventricular premature contractions were monitored by 24-hour dynamic electrocardiogram before and after treatment. The NIHSS score was evaluated before and after treatment.

Results

After treatment, the heart rate of the two groups was lower than that before treatment (P<0.05), and the heart rate of the study group was lower than that of the control group (P<0.05). The incidence of ventricular premature contraction in the study group was lower than that in the control group after treatment (P<0.05). After treatment, the NIHSS scores of the two groups were lower than those before treatment (P<0.05); the NIHSS scores of the observation group were lower than those of the control group after treatment (P<0.05).

Conclusion

Bisoprolol combined with benazepril can reduce the occurrence of ventricular premature contraction in patients with ventricular arrhythmia after intracerebral hemorrhage, effectively treat ventricular arrhythmia after intracerebral hemorrhage, which is conducive to the improvement of nerve function, and can be further popularized and applied.

Key words: Bisoprolol, Benazepril, Cerebral hemorrhage, Ventricular arrhythmia, Ventricular premature beat, Heart rate

Weiwei Yang, Xuedong Wang. Effect of bisoprolol combined with benazepril on ventricular arrhythmia after intracerebral hemorrhage[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2018, 06(02): 112-114.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhxzyxldzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-6568.2018.02.016

https://zhxzyxldzzz.cma-cmc.com.cn/EN/Y2018/V06/I02/112

Figures/Tables 2

References 12

[1]	蒋芳萍，宁靓，杨波. 比索洛尔联合常规三联疗法对风湿性心脏瓣膜病合并慢性心力衰竭患者疗效及相关指标的影响[J]. 中国药房，2016, 27(18): 2511-2513.
[2]	Tran T V, Cortez D. Clinical Application of the QRS－T Angle for the Prediction of Ventricular Arrhythmias in Patients with the Fontan Palliation[J]. Pediatr Cardiol, 2017, 38(5): 1-8.
[3]	张冬梅，张后民. 胺碘酮联用比索洛尔对左室肥厚的高血压患者QTd及VA的影响研究[J]. 重庆医学，2016, 45(25): 3546-3548.
[4]	刘军. 富马酸比索洛尔对慢性肺源性心脏病心律失常患者脑钠肽和C反应蛋白水平的影响[J]. 中国老年学杂志，2016, 36(9): 7-9.
[5]	师帅，耿彦婷，胡元会，等. 稳心颗粒联合比索洛尔治疗心力衰竭合并心律失常的系统评价[J]. 中国实验方剂学杂志，2016, 64(15): 216-219.
[6]	王云鹏，张云，孙一荣，等. 尼可地尔对急性ST段抬高型心肌梗死患者行急诊经皮冠状动脉介入治疗后室性心律失常的影响[J]. 中华心血管病杂志，2017, 45(8): 701-705.
[7]	胥良. 美托洛尔应用于高血压性心脏病患者对其QT间期离散度及室性心律失常的影响[J]. 重庆医学，2017, 32(A03): 325-327.
[8]	陈传俊，韩永生，陈晨，等. 早期复极及其形态与STEMI患者发生室性心律失常的关系[J]. 山东医药，2017, 57(17): 45-47.
[9]	Deniz A, Demir M. [Comments on 2015 ESC Guidelines for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death][J]. Turk Kardiyol Dern Ars, 2016, 44(1): 9-14.
[10]	双跃华，毛振立，于林. 醒脑静注射液在高血压脑出血患者微创血肿清除术后康复中的应用效果观察[J]. 山东医药，2017, 57(12): 93-95.
[11]	Kautzner J, Osmancˇ ík P. Summary of the 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Prepared by the Czech Society of Cardiology[J]. Revista Española De Cardiologiía, 2016, 69(2): 176-177.
[12]	刘吉园，牛小伟，张益铭，等. 急性ST段抬高型心肌梗死患者介入治疗前后T波峰末间期的变化过程及其与恶性室性心律失常的关系[J]. 中国循环杂志，2017, 32(2): 132-136.

组别	例数	心率(次/min)		室性期前收缩(次/1 000 QRS)
组别	例数	治疗前	治疗后	室性期前收缩(次/1 000 QRS)
对照组	30	96.43±9.61	93.12±7.64^a	25.76±5.65
研究组	30	97.25±8.56	86.21±15.91^ab	11.56±5.08^b

组别	例数	心率(次/min)		室性期前收缩(次/1 000 QRS)
组别	例数	治疗前	治疗后	室性期前收缩(次/1 000 QRS)
对照组	30	96.43±9.61	93.12±7.64^a	25.76±5.65
研究组	30	97.25±8.56	86.21±15.91^ab	11.56±5.08^b

组别	例数	治疗前	治疗后
对照组	30	22.32±4.65	12.43±3.53^a
研究组	30	21.84±5.36	7.43±3.34^ab

组别	例数	治疗前	治疗后
对照组	30	22.32±4.65	12.43±3.53^a
研究组	30	21.84±5.36	7.43±3.34^ab

[1]	Ying Chen, Yanli Chen. Causes of heart rate variability and perinatal outcomes in elderly pregnant women [J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2023, 19(03): 295-301.
[2]	Changlin Xu, Hao Cheng, Congguo Liu, Yun Gao, Yi Li, Yuanyuan Qiao, Sheng Chen. Comparative analysis of the effects of ROSA localized burr hole hematoma removal and empirical localized burr hole hematoma removal in the treatment of spontaneous intracerebral hemorrhage [J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(02): 97-101.
[3]	Zhengwen Diao, Yuchang Xu, Jie Zhang, Huajun Zhang, Qiulin Li, Hui Chen. Clinical analysis of β-aescinate sodium combined with glycerin fructose in the treatment of cerebral hemorrhage [J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(01): 32-37.
[4]	Bin Sun, Zongzhao He, Hao Wang, Ting Wang, Xiaoqin Liu. A study on the correlation between the severity and inflammatory response of hypertensive intracerebral hemorrhage patients undergoing surgery in the Xining area [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2023, 09(01): 62-68.
[5]	Zhengwei Liu, Lizhi Yi, Xilong Yin, Wenlong Kong, Zhisong Jiu, Wenyuan Zhang. Efficacy analysis of external drainage of conocephalic hematoma and neuroendoscopic surgery for senile hypertensive intracerebral hemorrhage in basal ganglia [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(05): 299-303.
[6]	Mo Yun, Maofang Li, Hao Wang, Dongyuan Liu. Clinical study of minimally invasive puncture and drainage combined with piracetam and urapidil in the treatment of hypertensive intracerebral hemorrhage in basal ganglia [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(05): 278-285.
[7]	Yong Zou, Yingjiang Gu, Hao Ding, Chenghao Yang, Minhui Chen, Yu Cai. Effects of puerarin on early inflammatory and oxidative stress responses involving the Nrf2/HO-1 and NF-κB signaling pathways after intracerebral hemorrhage in rat models [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(05): 271-277.
[8]	Xianjin Chen, Qinqin Wu, Changchun He, Qinghua Zhang. Research on constructing prognosis prediction model of intracerebral hemorrhage using multimodal medical data and machine learning [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(04): 193-198.
[9]	Ke Tan, Jinping Li, Yutao Peng, Wenqian Wu, Ziwen Yang, Yang Wang, Libo Tao, Chang Liu. Efficacy and health economic evaluation of robot-assisted stereotactic hematoma drainage for spontaneous intracerebral hemorrhage [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(04): 205-214.
[10]	Yongsheng Meng, Rong Yong, Xiaoli Ji, Yulong Zhao, Pengfei Zhao. Preventive effect of dexmedetomidine combined with sevoflurane on secondary injury after intracerebral hemorrhage and its neuroprotective mechanism [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(01): 44-50.
[11]	Jing Ding, Peiwen Li, Yingchun Xu. The application of Xingnao Kaiqiao acupuncture in severe neurological emergencies [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 161-164.
[12]	Qianwen Kong, Shan Liu, Caihong Zeng, Qingchun Zeng. Observational study of the effects of aerobic and resistance exercise on heart rate variability in patients with heart failure [J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2023, 11(03): 160-164.
[13]	Anna Shen, Jianxin Li, Fangchao Liu, Keyong Huang, Zhenyan Fu, Xiangfeng Lu, Dongfeng Gu. Association between resting heart rate and ten-year risk of cardiovascular disease in China [J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2023, 11(01): 5-11.
[14]	Tun Zhao, Jihua Xu, Youdi He, Ming Lu. Acute spontaneous trace amount cerebral hemorrhage misdiagnosed as cerebral infarction and nearly thrombolysis: a case report [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 369-372.
[15]	Ping Hu, Tengfeng Yan, Haizhu Zhou, Xingen Zhu. Advances in artificial intelligence be applied to early diagnose intracranial hemorrhage and hematoma segmentation [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 410-416.

Please choose a citation manager

Content to export