Clinical effect of metoprolol combined with trimetazidine in the treatment of coronary heart disease with heart failure

doi:10.3877/cma.j.issn.2095-6568.2018.02.015

Abstract

Abstract:

Objective

To investigate clinical effect of metoprolol combined with trimetazidine in the treatment of coronary heart disease with heart failure.

Methods

Eighty patients with CHF treated in Jieshou People's Hospital from July of 2016 to June of 2017 were divided into control group and experimental group according to the treatment methods. The control group received routine treatment, while the experimental group received metoprolol and trimetazidine on this basis. The therapeutic effects of the two groups were compared.

Results

The total effective rate of experimental group was 92.5%, higher than that of control group (75.0%), and there was significant difference between the two groups (P<0.05). After treatment, LVESD, LVEF and LVEDD of experimental group were better than those of control group (P<0.05).

Conclusion

Metoprolol combined with trimetazidine has a significant effect in the treatment of coronary heart disease with heart failure, can effectively improve the cardiac function of patients, is worthy of clinical promotion.

Key words: Heart failure, Coronary heart disease, Trimetazidine, Metoprolol

JinYing Zhao. Clinical effect of metoprolol combined with trimetazidine in the treatment of coronary heart disease with heart failure[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2018, 06(02): 109-111.

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References 11

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组别	n	显效	有效	无效	总有效率
对照组	40	15	15	10	75.0
实验组	40	17	20	3	92.5
χ²值	?	?	?	?	4.501
P值	?	?	?	?	0.034

组别	n	显效	有效	无效	总有效率
对照组	40	15	15	10	75.0
实验组	40	17	20	3	92.5
χ²值	?	?	?	?	4.501
P值	?	?	?	?	0.034

组别	n	LVEF(%)		LVESD(mm)		LVEDD(mm)
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	40	41.7±6.4	45.8±7.2^a	41.3±6.6	36.6±4.9^a	64.2±8.3	60.4±6.6^a
实验组	40	41.4±6.8	51.9±7.5^ab	41.2±6.4	32.8±5.4^ab	64.1±8.9	51.8±6.5^ab

组别	n	LVEF(%)		LVESD(mm)		LVEDD(mm)
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	40	41.7±6.4	45.8±7.2^a	41.3±6.6	36.6±4.9^a	64.2±8.3	60.4±6.6^a
实验组	40	41.4±6.8	51.9±7.5^ab	41.2±6.4	32.8±5.4^ab	64.1±8.9	51.8±6.5^ab

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