To observe the clinical effect of shenmai injection combined with benazepril in the treatment of chronic obstructive pulmonary disease (COPD) combined with chronic pulmonary heart disease (CPHD).

Seventy-nine patients with COPD combined with CPHD admitted to Henan Provincial People's Hospital from January of 2016 to October of 2017 were randomly divided into two groups. Patients in group A were treated with benazepril on the basis of conventional treatment, while patients in group B were treated with ginseng injection on the basis of the treatment of group A. The levels of LVEF, CO, FEV₁ and FVC% before and after treatment were compared between the two groups, and the total effective rate of the two groups was statistically calculated.

After treatment, LVEF, CO, FEV₁ and FVC% in group B were higher than those in group A (P<0.05). The total therapeutic efficiency of group B (97.50%) was higher than group A (84.62%), and the difference was statistically significant (P<0.05). No adverse reaction was observed in both groups.

Shenmai injection combined with benazepril has a better clinical efficacy in the treatment of COPD with CPHD, can effectively improve the cardiopulmonary function of patients, deserves the clinical expansion.