Comparison of two anesthesia methods for mitral valve replacement in patients with rheumatic heart disease

doi:10.3877/cma.j.issn.2095-6568.2018.04.006

Abstract

Abstract:

Objective

To compare the clinical efficacy of two anesthesia methods for mitral valve replacement in patients with rheumatic heart disease.

Methods

A total of 116 patients with rheumatic heart disease in Jiaozhou People's Hospital from March 2015 to April 2018 were selected. All patients underwent mitral valve replacement. They were divided into sevoflurane group (58 cases) and propofol group (58 cases) according to different anesthetic methods. The propofol group received propofol target controlled infusion anesthesia, and the sevoflurane group received sevoflurane inhalation anesthesia. The levels of myocardial enzymes (CK-MB, cTn I) at different time points and the time of consciousness disappearance were observed and compared between the two groups.

Results

After anesthesia, the disappearance of consciousness and extubation time of sevoflurane group were shorter than those of propofol group (P<0.05); serum cTnⅠ level of T₁-T₃ sevoflurane group was lower than that of propofol group (P<0.05); serum CK-MB level of T₃ sevoflurane group was lower than that of propofol group (P<0.05).

Conclusion

Compared with propofol target controlled infusion anesthesia, sevoflurane inhalation anesthesia can effectively shorten the time of consciousness loss and extubation and reduce myocardial injury in patients with rheumatic heart disease undergoing mitral valve replacement.

Key words: Sevoflurane, Whole-course inhalation anesthesia, Propofol, Whole-course target-controlled infusion anesthesia, Rheumatic heart disease, Mitral valve replacement

Qun Li. Comparison of two anesthesia methods for mitral valve replacement in patients with rheumatic heart disease[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2018, 06(04): 212-214.

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References 7

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组别	例数	拔管时间(min)	意识消失时间(s)
七氟醚组	58	12.38±3.52	36.92±10.47
丙泊酚组	58	22.03±3.38	48.32±10.09
t	?	15.060	5.971
P	?	0.000	0.000

组别	例数	拔管时间(min)	意识消失时间(s)
七氟醚组	58	12.38±3.52	36.92±10.47
丙泊酚组	58	22.03±3.38	48.32±10.09
t	?	15.060	5.971
P	?	0.000	0.000

组别	例数	cTnⅠ(ng/mL)				CK－MB(U/L)
组别	例数	T₀	T₁	T₂	T₃	T₀	T₁	T₂	T₃
七氟醚组	58	0.02±0.03	4.31±1.19	6.05±1.17	3.89±1.19	7.13±3.01	31.26±7.61	33.57±8.21	17.69±3.99
丙泊酚组	58	0.05±0.19	5.92±2.71^a	8.20±4.01^a	5.38±3.01^a	6.82±3.03	34.39±11.25	36.74±16.24	22.05±8.58^a

组别	例数	cTnⅠ(ng/mL)				CK－MB(U/L)
组别	例数	T₀	T₁	T₂	T₃	T₀	T₁	T₂	T₃
七氟醚组	58	0.02±0.03	4.31±1.19	6.05±1.17	3.89±1.19	7.13±3.01	31.26±7.61	33.57±8.21	17.69±3.99
丙泊酚组	58	0.05±0.19	5.92±2.71^a	8.20±4.01^a	5.38±3.01^a	6.82±3.03	34.39±11.25	36.74±16.24	22.05±8.58^a

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