探讨培哚普利和美托洛尔联合治疗老年心力衰竭合并室性心律失常的临床效果。

按入院顺序将88例老年心力衰竭合并室性心律失常患者分为对照组和观察组，各44例。对照组在常规治疗基础上接受培哚普利治疗，观察组接受培哚普利和美托洛尔联合治疗。比较两组患者治疗前后心率、左心室射血分数变化情况及不良反应发生率。

治疗后，两组患者心率均降低，左心室射血分数升高，差异有统计学意义(P<0.05)；观察组患者治疗后心率较对照组低，左室射血分数较对照组高，差异有统计学意义(P<0.05)。观察组不良反应发生率(4.55%)低于对照组(15.91%)，差异有统计学意义(P<0.05)。

采用培哚普利联合美托洛尔治疗老年心力衰竭合并室性心律失常患者，可显著改善心功能，不良反应少，值得临床推广应用。

To explore the efficacy of perindopril combined with metoprolol on elderly patients with heart failure complicated with ventricular arrhythmia.

According to the order of admission, 88 elderly patients with heart failure and ventricular arrhythmia were divided into control group and observation group, 44 cases in each group. The control group was treated with perindopril on the basis of routine treatment, while the observation group was treated with perindopril and metoprolol. The changes of heart rate, left ventricular ejection fraction and the incidence of adverse reactions were compared between the two groups before and after treatment.

After treatment, the heart rate of the two groups decreased, left ventricular ejection fraction increased, the difference was statistically significant (P<0.05); after treatment, the heart rate of the observation group was lower than that of the control group, and left ventricular ejection fraction was higher than that of the control group, the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group (4.55%) was lower than that in the control group (15.91%), and the difference was statistically significant (P<0.05).

For elderly patients with heart failure and ventricular arrhythmia, perindopril combined with metoprolol can significantly improve cardiac function with fewer adverse reactions, which is worthy of clinical application.