Abstract:
Objective To observe the efficacy and safety of bisoprolol combined with low molecular weight heparin in the treatment of unstable angina pectoris.
Methods Eighty-nine patients with unstable angina pectoris were randomly divided into two groups (A=44, B=45). Group A was treated with bisoprolol on the basis of routine treatment, and group B was treated with low molecular weight heparin on the basis of group A. The total effective rate and the incidence of adverse reactions were counted, and the levels of hemorheology and cardiac function were measured before and after treatment.
Results The total effective rate (81.82%) in group A was lower than that in group B (95.56%) and P<0.05. There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). The hemorheological indexes in group B were lower than those in group A (P<0.05). The levels of LVESD and LVEDD in group B were lower than those in group A after treatment, but the levels of LVEF were higher.
Conclusion Bisoprolol combined with low molecular weight heparin can effectively improve coagulation status and cardiac function in patients with unstable angina pectoris, and does not increase the risk of drug use, which can be promoted in clinical practice.
Key words:
Unstable angina pectoris,
Bisoprolol,
Low molecular heparin,
Hemorheology
Yuanlin Luo, Yanmei Xu, Linling Li, Jinlong Yang. Efficacy and safety of bisoprolol combined with low molecular heparin in the treatment of unstable angina pectoris[J]. Chinese Journal of Heart and Heart Rhythm(Electronic Edition), 2018, 06(01): 52-54.