To explore the efficacy of perindopril combined with metoprolol on elderly patients with heart failure complicated with ventricular arrhythmia.

According to the order of admission, 88 elderly patients with heart failure and ventricular arrhythmia were divided into control group and observation group, 44 cases in each group. The control group was treated with perindopril on the basis of routine treatment, while the observation group was treated with perindopril and metoprolol. The changes of heart rate, left ventricular ejection fraction and the incidence of adverse reactions were compared between the two groups before and after treatment.

After treatment, the heart rate of the two groups decreased, left ventricular ejection fraction increased, the difference was statistically significant (P<0.05); after treatment, the heart rate of the observation group was lower than that of the control group, and left ventricular ejection fraction was higher than that of the control group, the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group (4.55%) was lower than that in the control group (15.91%), and the difference was statistically significant (P<0.05).

For elderly patients with heart failure and ventricular arrhythmia, perindopril combined with metoprolol can significantly improve cardiac function with fewer adverse reactions, which is worthy of clinical application.