To investigate the effect of interventional therapy combined with comprehensive rehabilitation training on the exercise tolerance and clinical prognosis in patients with coronary artery disease.

From July 2015 to August 2016 in 300 cases of coronary heart disease patients in our hospital to receive treatment as the research object, randomly divided into A group (n=100), B group (n=100) and C group (n=100), the A group with drug treatment, patients in group B only with interventional surgery, group C patients the implementation of interventional therapy combined with rehabilitation training for treatment.The exercise tolerance, heart function and the quality of life in Minnesota were compared between the three groups.

C group of patients with total exercise time, ST segment of 1mm time, maximum ST segment depression, angina, time to exercise and exercise tolerance was significantly better than the other two groups, compare (P<0.05); there are some differences between the three groups before and after treatment in patients with LVEF, A/E, LVEDd and other indicators of cardiac function existence there are also significant differences, differences between groups and C group (P<0.05); the quality of life of patients was significantly better than that of A group and B group, significant difference (P<0.05).

Interventional therapy combined with comprehensive rehabilitation training can improve the patient′s cardiac function and exercise tolerance to a certain extent, and improve the quality of life of the patients.

The relationship between the change of QT dispersion and ventricular arrhythmia in patients with acute stroke was analyzed.

A total of 80 acute stroke patients treated at the People′s Hospital of Shouguang City from May 2016 to October 2017 were selected and 40 middle-aged and elderly health checkups who were examined in the same hospital during the same period were selected as the study subjects. According to the type of stroke, they were divided into two groups: group A (hemorrhagic stroke, 32 cases) and B (ischemic stroke, 48 cases). All 40 healthy subjects were included in group C. Three groups of electrocardiographs were given for detection, and two groups of stroke patients were monitored by electrocardiograph. Observed the difference of QT interval dispersion, the incidence of ventricular arrhythmia and the dispersion of QT interval in patients with acute stroke.

The QT interval dispersion in group A was significantly higher than that in group B and C (P<0.05). There was no significant difference between group B and group C (P>0.05). The incidence of ventricular arrhythmia in group A was higher than that in group B (P<0.05). The QT dispersion in patients with acute stroke in ventricular arrhythmia group was significantly higher than that in patients with acute stroke in the acute group, and the difference was statistically significant. Significance (P<0.05).

Patients with hemorrhagic stroke have a higher risk of ventricular arrhythmias. If patients with acute stroke are associated with an abnormal increase in QT interval dispersion, they should be alert to ventricular arrhythmias.

To study the difference of brachial - ankle pulse wave conduction velocity (baPWV) between young essential hypertensive and normal blood pressure people, and to explore the correlation of baPWV with cardiovascular risk factors.

Enrolled 120 newly diagnosed hypertension outpatients in Changping Traditonal Chinese Medicine Hospital during May 2015 to December 2016, as hypertension group.and 120 young healthy normal blood pressure people of medical examination center as non-hypertension group .Collected the questionnaire, and test of liver and kidney function, blood lipids, blood glucose, uric acid, urine trace albumin and baPWV respectively.analyzed the baPWV of two groups, and the baPWV by blood pressure grades. Multiple linear regression analysis to explicit the related factors of baPWV in young hypertension patients.

(1) the baPWV in hypertension group was higher than in non-hypertensive group with statistically significant [right baPWV: (1 596.65±122.35) vs (1 350.95±63.37), P<0.05; left baPWV: (1 605.70±147.38) vs (1 340.60±64.03), P<0.05]; (2)in hypertension group, the baPWV increased with the blood pressure grade (Grade- 3 hypertension baPWV>Grade-2 hypertension baPWV>Grade-1 hypertension baPWV); (3) there was a correlation between baPWV and systolic blood pressure, diastolic blood pressure and urinary trace albumin (P<0.05), and multiple linear-regression analysis suggested that blood pressure was a related factor affecting baPWV.

The baPWV in hypertension group was higher than that in the non-hypertension group, suggested that early blood vessel damage was present in young hypertension patients, and the baPWV also increased as the blood pressure level increasing.Blood pressure is associated with the baPWV, the positive control of hypertension, could improve the baPWV, the arterial stiffness, and prevent the cardiovascular disease in advance.

To analyze the effect of enalapril maleate folic acid tablet in the treatment of elderly patients with chronic heart failure on the level of NT-pro BNP and Hcy.

A total of 60 elderly patients with chronic heart failure admitted to our hospital from May 2016 to May 2017 were selected.The patients were divided into 2 groups according to the random number table method.The study group was treated with enalapril maleate folic acid tablets.The control group was treated with enalapril.The levels of NT-pro BNP and Hcy in patients after treatment were analyzed, and the levels of NT-pro BNP and Hcy before and after treatment were observed in patients with different grades of cardiac function.

After treatment, NT-pro BNP and Hcy levels in the study group were lower than those in the control group (P<0.05), and the difference was significant.Before treatment, NT-pro BNP and Hcy levels increased with the cardiac functional class.Increase(P<0.05), significant difference.

The treatment of elderly patients with chronic heart failure with enalapril maleate folic acid tablets can improve the patients′ NT-pro BNP and Hcy levels.

To analyze the level of plasma brain natriuretic peptide (BNP) and the related factors in the patients with chronic heart failure after anti heart failure treatment.

The subjects selected from our hospital in 45 cases of elderly patients with chronic heart failure from October 2014 to December 2016 in Guizhou Cancer Hospital, the clinical data of all patients were analyzed retrospectively, and the patients as the observation group, and 45 healthy persons in our hospital were selected as control group in this study. Two groups of subjects of systolic blood pressure, diastolic blood pressure, pulmonary congestion, pulmonary hypertension, compare the left ventricular ejection fraction, and affecting factors of the related results were analyzed.Comparison of the patients in the observation group before after anti heart failure treatment and treatment level of BNP patients, and to assess the resistance the treatment of heart failure.

There were significant differences in systolic blood pressure, diastolic blood pressure, pulmonary congestion, pulmonary hypertension and left ventricular ejection fraction between the two groups(P<0.05). The levels of BNP in the observation group were compared before and after treatment, and the difference was statistically significant before and after treatment (P<0.05).

Hypotension, pulmonary congestion and other related factors are independent risk factors of chronic heart failure. After the treatment of anti heart failure, the BNP level of patients can be significantly improved.

To explore the clinical efficacy of clopidogrel combined aspirin for acute myocardial infarction.

From May 2016 to August 2017, 200 cases of patients with acute myocardial infarction (mi) in this study, based on different methods of treatment is divided into two categories, first using a single aspirin therapy, group b is on the basis of this part with clopidogrel, curative effect between the comparison groups.

The clinical indexes of group b were superior to that of group a. However, the incidence of complications was lower, and the total effective rate of treatment was 98.00%, significantly higher than 84.00% in group a, and the difference was statistically significant (P<0.05).

In patients with acute myocardial infarction with clopidogrel in combination with aspirin treatment, not only can achieve good curative effect, and can effectively improve the patient′s clinical symptoms, high security, is worth further promotion and application in clinic.

To study the correlation between the treatment of hypertension and the severity of ischemic stroke.

Three hundred patients with ischemic stroke and hypertension were selected from August 2015 to August 2017.After admission, the patients were divided into mild stroke and severe stroke according to the NIHSS score.To analyze the specific conditions of hypertension treatment and the severity of ischemic stroke, and to summarize the correlation between the two.

In the treatment of hypertension, the regular treatment rate of patients with mild stroke was higher than that of severe stroke patients.The rate of unknowing, non treatment and irregular treatment were lower than those of severe stroke(P<0.05). Compared with regular treatment patients, patients with unknowing, untreated or irregular treatment tended to have severe stroke(P<0.05).

There is a significant correlation between the treatment of hypertension and the severity of ischemic stroke.The regulation of hypertension can reduce the severity of ischemic stroke.

To study the coronary artery stenosis and its myocardial function by multi-slice spiral CT coronary angiography.

Sixty-eight patients with coronary artery stenosis admitted in our hospital from October 2016 to August-2017 were selected as the subjects.A total of 476(580 segments)coronary arteries were evaluated.Selective coronary angiography and multi-slice spiral CT coronary angiography were performed in patients with coronary artery stenosis.The results of coronary angiography and myocardial function were observed.

Two hundred thirty-two segments were detected by selective coronary angiography, including 172 mild stenosis, 46 moderate stenosis and 14 severe stenosis, 230 segment stenosis, 171 mild stenosis, 45 moderate stenosis, 14 severe stenosis and 98.74%sensitivity(P>0.05). The cardiac output(CO)(3.24±0.79)L/min, stroke output(SV)(46±11.7)ml.

Multislice spiral CT coronary angiography is of high sensitivity in the diagnosis of coronary artery stenosis and can accurately assess the myocardial function of patients.

To evaluate the effect of the treatment of children with arrhythmia in the treatment of middle and small dose amiodarone, and to analyze the changes of thyroid hormone levels in children with drug use.

The 116 children with arrhythmia treated in the Chinese Hospital of Linyi County from August 2016 to August 2017 were selected as study subjects. According to the random number table method, they were randomly divided into a control group and an observation group, 58 cases in each group. Select propafenone hydrochloride tablets and small doses of amiodarone hydrochloride to treat the effects of abnormal heart rhythm in the two groups of patients.Compare the changes of thyroid hormone levels and adverse drug reactions before and after treatment.

The effect of arrhythmia treatment was observed, the effective rate of treatment in the observation group(96.55%)was compared with the control group(86.21%), and the difference was statistically significant(P<0.05). There was no significant difference in thyroid hormone levels between the two groups before and after treatment(P>0.05). The incidence of adverse drug reactions(ADR)in the observation group(5.17%)was significantly higher than that in the control group(17.24%), and the difference was statistically significant.

In the treatment of children with arrhythmia, small dose of amiodarone has positive effect on improving the symptoms of arrhythmia, the incidence of adverse reaction is low, and there is no obvious effect on the level of thyroid hormone in children.It should be popularized and applied in clinical practice.

Through the clinical analysis of patients with persistent atrial fibrillation and paroxysmal atrial fibrillation in Emergency Department, we provide the basis for clinical prevention and treatment.

Fifty-five cases with atrial fibrillation were continuously selected from Emergency Department of Peking University People′s Hospital from March 2016 to October 2016.According to the characteristics of atrial fibrillation, the patients were divided into persistent atrial fibrillation group and paroxysmal atrial fibrillation group, comparing and analyzing the clinical data using statistical method.

There was no significant difference in clinical baseline data between patients with persistent atrial fibrillation and paroxysmal atrial fibrillation, but most of the patients with atrial fibrillation were female and older, and the proportion of hypertension and (or) coronary heart disease was higher.

Advanced age, female, high blood pressure and (or) coronary heart disease were the risk factor of atrial fibrillation, but there was no significant difference between the patients with persistent atrial fibrillation and paroxysmal atrial fibrillation.

To study the predictors of slow flow of coronary artery, To provide reference for the prevention, diagnosis and treatment of CSFP.

The clinical data of 60 cases of analysis from October 2012 to June 2017 due to "chest pain" and other reasons in the Shanxi hospital for coronary angiography of epicardial coronary artery stenosis was less than 40% were retrospectively analyzed, they were divided into CSFP group (CSFP group, n=30) and normal one group (control group, n=30) two groups according to whether the patients had coronary slow flow phenomenon.The general data and laboratory examination of the two groups were statistically analyzed, the predictors of slow flow of coronary artery were Logistic multivariate regression analyzed.

The proportion of men and smoking history of the CSFP group were significantly higher (P<0.05), the age and smoking index were significantly higher (n<0.05), the smoking duration was significantly longer (n<0.05), the high-density lipoprotein were significantly lower (n<0.05), and the creatinine, uric acid and hemoglobin levels were significantly higher than the control group (n<0.05), but the differences of ejection fraction, history of hypertension and diabetes, total cholesterol, triglyceride, low density lipoprotein, alanine aminotransferase, aspartate aminotransferase, C reactive protein, fasting blood glucose, serum potassium, CK-MB, troponin, brain natriuretic peptide, platelet counts, white blood cell counts between the two groups were not significant (n>0.05). Logistic multivariate regression analysis showed that the related predictors of coronary slow flow phenomenon included tobacco age, uric acid and high-density lipoprotein (n<0.05).

tobacco age, uric acid level and Low high density lipoprotein level were the predictors of CSFP.

The aim of this study was to analysis the prevalence, risk factor of frailty in elderly patients with chronic heart failure.

The elderly patients with chronic heart failure in General Hospital of Guangzhou Military Command of PLA from 2013 to 2017 were enrolled in the study.The demographic characteristics and medical record data were collected.All patients received frailty assessment with Fried criteria.A total of 371 patients aged 65-96(80.5±6.0)years were included in this study.

The prevalence rate of frailty was 21.3%, with 16.4% and 26.4% in patients of 65-79 and ≥ 80 years respectively(P<0.05). The prevalence of frailty in elderly patients with chronic heart failure with renal insufficiency and cerebrovascular disease was significantly higher in with the two diseases than without (P<0.05). The prevalence of frailty increased with the number of major complications in elderly patients with chronic heart failure.Multivariate Logistic regression analysis indicated that elderly, renal insufficiency, cerebrovascular disease and NYHA classification were significantly associated with frailty (P<0.05).

The prevalence rate of frailty in patients was increased with age and the number of major complications.The elderly, renal insufficiency, cerebrovascular disease and NYHA classification may be the independent risk factors for frailty in elderly patients with chronic heart failure.

To investigate the effect of ambulatory electrocardiogram (ECG) in the diagnosis of senile arrhythmia.

One hundred and eighty elderly patients with arrhythmia examined in our hospital from January 2016 to December were selected as subjects.They received routine electrocardiogram and dynamic electrocardiogram examination, and their clinical diagnostic effects were compared.

The detection rate of dynamic electrocardiogram was significantly higher than that of conventional dynamic electrocardiogram, and the type of disease detection was more detailed (P<0.05).

For the diagnosis of old arrhythmia, the diagnostic rate of dynamic electrocardiogram is high and the clinical value is high.

To investigate the anesthetic method and anesthetic effect of cesarean section in pregnant women with cardiac disease.

60 pregnant women with heart disease were randomly selected from our hospital in February 2017-2018 February.The patients were randomly divided into general anesthesia group and epidural anesthesia group.30 cases each.The vital signs of the two groups were compared, and the neonatal Apgar score was compared.

before operation, the heart rate of the general anesthesia group was(97.6±4.4)times/min, and the epidural anesthesia group was(77.3±5.6)times/min(P<0.05). The heart rate of patients in general anesthesia group before and after fetal removal was significantly higher than that before epidural anesthesia, which was also higher than that before anesthesia, P<0.05.The central venous pressure of the patients in the general anesthesia group was(109.8±4.2)P/mmHg, which was higher than that before and before the operation, and was also higher than that in the epidural anesthesia group(P<0.05). In general anesthesia group, neonatal Apgar score was normal in 22 cases, epidural anesthesia group in 29 cases, P<0.05.

continuous epidural anesthesia is more conducive to stabilize the vital signs of patients, and has a higher advantage.

To investigate the clinical efficacy of trimetazidine in the treatment of coronary heart disease and to observe the changes of ultrasonic parameters.

From August 2016 to August 2017, 120 patients with coronary heart disease were randomly divided into control group and observation group. 60 patients in control group were treated with routine therapy.In the observation group, 60 patients were treated with trimetazidine on the basis of routine treatment.

There was no significant difference in SVG COCI and EF between the two groups before treatment(P>0.05). After treatment, the indexes in the observation group were significantly higher than those in the control group (P<0.05). Meanwhile, the improvement of ultrasound indexes in the observation group was significantly better than that in the control group (P<0.05).

In the clinical treatment of coronary heart disease, the effect of trimetazidine was better than that of routine treatment.The survey of patients′ satisfaction showed that the observation group was superior to the control group, and the ultrasonic indexes of the patients had obvious changes.It is beneficial to the recovery of health of patients with coronary heart disease, and should be further popularized and applied clinically.

To explore the role of comfortable nursing in the clinical nursing of elderly patients with chronic heart failure.

108 elderly patients with chronic heart failure received in our hospital from August 2016 to August 2017 were randomly divided into the observation group and the control group, 54 cases in each group.The observation group was given comfortable nursing, while the control group was given traditional clinical nursing to observe the nursing effect.

the incidence of complications in the observation group was lower than that of the control group, and the quality of life score of the patients was higher than that of the control group, the difference was significant(P<0.05).

the application of comfortable nursing in the elderly patients with chronic heart failure can reduce the complications, promote the recovery and improve the quality of life of the patients.

On the patients with acute myocardial infarction, the effect of high quality nursing intervention was carried out in the course of treatment.

The number of patients in this study were 90 cases, hospitalization time of patients between March 2016 ~2017 March, the patients were divided into two groups were compared, the observation group and the control group and the control group with routine nursing intervention, the observation group used high quality nursing intervention, compare the effect.

The effective rate of the observation group is 6.67% higher than the control group, while patients in the observation group after treatment of diastolic time, E peak deceleration time, maximum velocity and diastolic maximum velocity was better than the control group, the patients in the observation group satisfaction was significantly higher than the control group 11.11%(P<0.05).

Patients with acute myocardial infarction, the implementation of whole quality nursing intervention is more effective, which can effectively improve the clinical indicators of patients, and relieve their clinical symptoms, so as to ensure their health.